Taraxacum officinale herb health benefit, also known as dandelion herb
Chrysanthemum, dandelion, and mugwort belong to the Compositae (Asteraceae) family. Chrysanthemum and dandelion were frequently cosensitized with mugwort in the general population with respiratory allergic diseases.
Taraxacum officinale benefit
Taraxacum officinale contains anti-angiogenic, anti-inflammatory and anti-nociceptive
activities through its inhibition of NO production and COX-2 expression and/or
its antioxidative activity.
Taraxacum officinale and
cancer
Evaluation of aqueous extracts of
Taraxacum officinale on growth and invasion of breast and prostate cancer cells.
Int J Oncol. 2008 May; Sigstedt SC, Hooten CJ, Callewaert MC, Jenkins AR, Romero
AE, Pullin MJ, Kornienko A, Lowrey TK, Slambrouck SV, Steelant WF.
Laboratory of Biochemical and Biomedical Research, Department of Chemistry, New
Mexico Tech, Socorro, NM 87801, USA.
Plants of the genus Taraxacum, commonly known as dandelions, have a history of
use in Chinese, Arabian and Native American traditional medicine, to treat a
variety of diseases including cancer. To date, however, very few studies have
been reported on the anti-carcinogenic activity of Taraxacum officinale. In the
present study, three aqueous extracts were prepared from the mature leaves,
flowers and roots, and investigated on tumor progression related processes such
as proliferation and invasion. Our results show that the crude extract of
Taraxacum officinale leaf decreased the growth of MCF-7/AZ breast cancer cells
in an ERK-dependent manner, whereas the aqueous extracts of Taraxacum officinale
flower and root had no effect on the growth of either cell line. Furthermore,
Taraxacum officinale root was found to block invasion of MCF-7/AZ breast cancer
cells while Taraxacum officinale leaf blocked the invasion of LNCaP prostate
cancer cells, into collagen type I. This study provides new scientific data on
TO and suggests that Taraxacum officinale extracts or individual components
present in the extracts may be of value as novel anti-cancer agents.
Cholesterol, lipids
Hypolipidemic and Antioxidant Effects of Dandelion (Taraxacum officinale) Root
and Leaf on Cholesterol-Fed Rabbits.
Int J Mol Sci. 2010 Jan 6; Pohang Center for Evaluation of Biomaterials,
Pohang 790-834, Korea;
Dandelion (Taraxacum officinale), an oriental herbal medicine, has been shown
to favorably affect choleretic, antirheumatic and diuretin properties. Recent
reports have indicated that excessive oxidative stress contributes to the
development of atherosclerosis-linked metabolic syndrome. The objective of this
current study was to investigate the possible hypolipidemic and antioxidative
effects of dandelion root and leaf in rabbits fed with a high-cholesterol diet.
A group of twenty eight male rabbits was divided into four subgroups; a normal
diet group, a high-cholesterol diet group, a high-cholesterol diet with 1% (w/w)
dandelion leaf group, and a high-cholesterol diet with 1% (w/w) dandelion root
group. After the treatment period, the plasma antioxidant enzymes and lipid
profiles were determined. Our results show that treatment with dandelion root
and leaf positively changed plasma antioxidant enzyme activities and lipid
profiles in cholesterol-fed rabbits, and thus may have potential hypolipidemic
and antioxidant effects. Dandelion root and leaf could protect against oxidative
stress linked atherosclerosis and decrease the atherogenic index.
Lutein in Taraxacum officinale herb
Lutein epoxide has been isolated from petals of dandelion (Taraxacum officinale
F. Weber ex Wiggers)
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